Hedgehog Pathway Blockade Inhibits Melanoma Cell Growth in Vitro and in Vivo

Previous reports have demonstrated a role for hedgehog signaling in melanoma progression, prompting us to explore the therapeutic benefit of targeting this pathway in melanoma. We profiled a panel of human melanoma cell lines and control melanocytes for altered expression of hedgehog pathway members...

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Bibliografiske detaljer
Main Authors: O’Reilly, Kathryn E., Vega-Saenz de Miera, Eleazar, Segura, Miguel F., Friedman, Erica, Poliseno, Laura, Han, Sung Won, Zhong, Judy, Zavadil, Jiri, Pavlick, Anna, Hernando, Eva, Osman, Iman
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854019/
https://ncbi.nlm.nih.gov/pubmed/24287465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph6111429
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