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Inherited common variants in mitochondrial DNA and invasive serous epithelial ovarian cancer risk
BACKGROUND: Mitochondria are the site of oxidative phosphorylation, a process which generates reactive oxygen species (ROS). Elevated ROS levels can lead to oxidative stress, a cellular state implicated in carcinogenesis. It is hypothesized that alternations in mitochondrial (MT) DNA, including heri...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3854008/ https://ncbi.nlm.nih.gov/pubmed/24148579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-6-425 |
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