Bactericidal activity of PA-824 against Mycobacterium tuberculosis under anaerobic conditions and computational analysis of its novel analogues against mutant Ddn receptor

BACKGROUND: The resurgence of multi-drug resistant tuberculosis (MDR-TB) and HIV associated tuberculosis (TB) are of serious global concern. To contain this situation, new anti-tuberculosis drugs and reduced treatment regimens are imperative. Recently, a nitroimidazole, PA-824, has been shown to be...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Somasundaram, Sulochana, Anand, Ramaian Santhaseela, Venkatesan, Perumal, Paramasivan, Chinnambedu N
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853930/
https://ncbi.nlm.nih.gov/pubmed/24083570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-13-218
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