Docking studies on novel analogues of 8 methoxy fluoroquinolones against GyrA mutants of Mycobacterium tuberculosis

BACKGROUND: Fluoroquinolone resistance is a serious threat in the battle against the treatment of multi drug resistant tuberculosis (MDR-TB) and extensively drug resistant tuberculosis (XDR-TB). Fluoroquinolone resistant isolates from India had shown to have evolved several mutants in the quinolone...

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Autors principals: Anand, RS, Somasundaram, Sulochana, Doble, Mukesh, Paramasivan, CN
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3298726/
https://ncbi.nlm.nih.gov/pubmed/22152119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-11-47
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