Transcriptional control of DNA replication licensing by Myc

The c-myc protooncogene encodes the Myc transcription factor, a global regulator of fundamental cellular processes. Deregulation of c-myc leads to tumorigenesis, and c-myc is an important driver in human cancer. Myc and its dimerization partner Max are bHLH-Zip DNA binding proteins involved in trans...

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Main Authors: Valovka, Taras, Schönfeld, Manuela, Raffeiner, Philipp, Breuker, Kathrin, Dunzendorfer-Matt, Theresia, Hartl, Markus, Bister, Klaus
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853707/
https://ncbi.nlm.nih.gov/pubmed/24309437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03444
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