KRAS and BRAF Mutations in 203 Esophageal Squamous Cell Carcinomas: Pyrosequencing Technology and Literature Review

BACKGROUND: Epidermal growth factor receptor (EGFR) signaling is one of the most promising targets for molecular-targeted therapies in esophageal squamous cell carcinoma (ESCC). Thus, the molecular diagnosis of KRAS and BRAF mutations is clinically important in therapeutic decision making. However,...

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Main Authors: Shigaki, Hironobu, Baba, Yoshifumi, Watanabe, Masayuki, Miyake, Keisuke, Murata, Asuka, Iwagami, Shiro, Ishimoto, Takatsugu, Iwatsuki, Masaaki, Yoshida, Naoya, Baba, Hideo
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2012
Teme:
Translational Research and Biomarkers
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853643/
https://ncbi.nlm.nih.gov/pubmed/23274581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-012-2819-z
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