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Genetic myostatin decrease in the golden retriever muscular dystrophy model does not significantly affect the ubiquitin proteasome system despite enhancing the severity of disease

Recent studies suggest that inhibiting the protein myostatin, a negative regulator of skeletal muscle mass, may improve outcomes in patients with Duchenne muscular dystrophy by enhancing muscle mass. When the dystrophin-deficient golden retriever muscular dystrophy (GRMD) dog was bred with whippets...

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Sonraí Bibleagrafaíochta
Main Authors: Cotten, Steven W, Kornegay, Joe N, Bogan, Daniel J, Wadosky, Kristine M, Patterson, Cam, Willis, Monte S
Formáid: Artigo
Teanga:Inglês
Foilsithe: e-Century Publishing Corporation 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853423/
https://ncbi.nlm.nih.gov/pubmed/24349620
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