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Regulation of the calpain and ubiquitin proteasome systems in a canine model of muscular dystrophy

INTRODUCTION: Previous studies have tested the hypothesis that calpain and/or proteasome inhibition is beneficial in Duchenne Muscular Dystrophy, based largely on evidence that calpain and proteasome activities are enhanced in the mdx mouse. METHODS: mRNA expression of ubiquitin proteasome and calpa...

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Detalhes bibliográficos
Main Authors: Wadosky, Kristine M., Li, Luge, Rodríguez, Jessica E., Min, JinNa, Bogan, Dan, Gonzalez, Jason, Patterson, Cam, Kornegay, Joe N., Willis, Monte
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175337/
https://ncbi.nlm.nih.gov/pubmed/21826685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mus.22125
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