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Higher Expression of Receptor Tyrosine Kinase Axl, and Differential Expression of its Ligand, Gas6, Predict Poor Survival in Lung Adenocarcinoma Patients

BACKGROUND: Downstream activation through receptor tyrosine kinases (RTKs) plays important roles in carcinogenesis. In this study, we assessed the clinical involvement of Axl, an RTK, and its ligand, Gas6, in surgically treated lung adenocarcinoma. METHODS: Axl and Gas6 mRNA and protein expression l...

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Detalhes bibliográficos
Main Authors: Ishikawa, Masashi, Sonobe, Makoto, Nakayama, Ei, Kobayashi, Masashi, Kikuchi, Ryutaro, Kitamura, Jiro, Imamura, Naoto, Date, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853411/
https://ncbi.nlm.nih.gov/pubmed/23242819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-012-2795-3
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