Tissue resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes

Despite accumulating evidence suggesting local self-maintenance of tissue macrophages in the steady state, the dogma remains that tissue macrophages derive from monocytes. Using parabiosis and fate mapping approaches, we confirmed that monocytes do not show significant contribution to tissue macroph...

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Detalhes bibliográficos
Main Authors: Hashimoto, Daigo, Chow, Andrew, Noizat, Clara, Teo, Pearline, Beasley, Mary Beth, Leboeuf, Marylene, Becker, Christian D., See, Peter, Price, Jeremy, Lucas, Daniel, Greter, Melanie, Mortha, Arthur, Boyer, Scott W., Forsberg, E. Camilla, Tanaka, Masato, van Rooijen, Nico, García-Sastre, Adolfo, Stanley, E. Richard, Ginhoux, Florent, Frenette, Paul S., Merad, Miriam
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853406/
https://ncbi.nlm.nih.gov/pubmed/23601688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.04.004
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