Bone marrow CD169(+) macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche

Hematopoietic stem cells (HSCs) reside in specialized bone marrow (BM) niches regulated by the sympathetic nervous system (SNS). Here, we have examined whether mononuclear phagocytes modulate the HSC niche. We defined three populations of BM mononuclear phagocytes that include Gr-1(hi) monocytes (MO...

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Detalhes bibliográficos
Main Authors: Chow, Andrew, Lucas, Daniel, Hidalgo, Andrés, Méndez-Ferrer, Simón, Hashimoto, Daigo, Scheiermann, Christoph, Battista, Michela, Leboeuf, Marylene, Prophete, Colette, van Rooijen, Nico, Tanaka, Masato, Merad, Miriam, Frenette, Paul S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039855/
https://ncbi.nlm.nih.gov/pubmed/21282381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20101688
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