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Adaptive Clinical Trial Designs for Simultaneous Testing of Matched Diagnostics and Therapeutics

A critical challenge in the development of new molecularly targeted anticancer drugs is the identification of predictive biomarkers and the concurrent development of diagnostics for these biomarkers. Developing matched diagnostics and therapeutics will require new clinical trial designs and methods...

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Hlavní autoři: Scher, Howard I., Nasso, Shelley Fuld, Rubin, Eric H., Simon, Richard
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853353/
https://ncbi.nlm.nih.gov/pubmed/22046024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-1105
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