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Glyceraldehyde-3-phosphate dehydrogenase antisense oligodeoxynucleotides protect against cytosine arabinonucleoside-induced apoptosis in cultured cerebellar neurons.

Cytosine arabinonucleoside (AraC) is a pyrimidine antimetabolite that kills proliferating cells by inhibiting DNA synthesis and, importantly, is also an inducer of apoptosis. We recently reported that age-induced apoptotic cell death of cultured cerebellar neurons is directly associated with an over...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Ishitani, R, Chuang, D M
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38533/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8790435/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.18.9937
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