Lithium Down-regulates Histone Deacetylase 1 (HDAC1) and Induces Degradation of Mutant Huntingtin

Lithium is an effective mood stabilizer that has been clinically used to treat bipolar disorder for several decades. Recent studies have suggested that lithium possesses robust neuroprotective and anti-tumor properties. Thus far, a large number of lithium targets have been discovered. Here, we repor...

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Dades bibliogràfiques
Autors principals: Wu, Shuai, Zheng, Shui-Di, Huang, Hong-Ling, Yan, Li-Chong, Yin, Xiao-Fei, Xu, Hai-Neng, Zhang, Kang-Jian, Gui, Jing-Hua, Chu, Liang, Liu, Xin-Yuan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853296/
https://ncbi.nlm.nih.gov/pubmed/24165128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.479865
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