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Lithium Down-regulates Histone Deacetylase 1 (HDAC1) and Induces Degradation of Mutant Huntingtin

Lithium is an effective mood stabilizer that has been clinically used to treat bipolar disorder for several decades. Recent studies have suggested that lithium possesses robust neuroprotective and anti-tumor properties. Thus far, a large number of lithium targets have been discovered. Here, we repor...

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Detalhes bibliográficos
Main Authors: Wu, Shuai, Zheng, Shui-Di, Huang, Hong-Ling, Yan, Li-Chong, Yin, Xiao-Fei, Xu, Hai-Neng, Zhang, Kang-Jian, Gui, Jing-Hua, Chu, Liang, Liu, Xin-Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853296/
https://ncbi.nlm.nih.gov/pubmed/24165128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.479865
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