Binding of a Sialic Acid-recognizing Lectin Siglec-9 Modulates Adhesion Dynamics of Cancer Cells via Calpain-mediated Protein Degradation

Although regulatory mechanisms for immune cells with inhibitory signals via immunoreceptor tyrosine-based inhibitory motifs are well known, signals transduced via interaction between Siglecs and sialyl compounds on their counterreceptors into target cells have not been reported to date. In this stud...

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Bibliographic Details
Main Authors: Sabit, Ilhamjan, Hashimoto, Noboru, Matsumoto, Yasuyuki, Yamaji, Toshiyuki, Furukawa, Keiko, Furukawa, Koichi
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Glycobiology and Extracellular Matrices
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853289/
https://ncbi.nlm.nih.gov/pubmed/24145038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.513192
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