Phosphorylation of the Cryptochrome 1 C-terminal Tail Regulates Circadian Period Length

The Cryptochrome (CRY) proteins are critical components of the mammalian circadian clock and act to rhythmically repress the activity of the transcriptional activators CLOCK and BMAL1 at the heart of the clock mechanism. The CRY proteins are part of a large repressive complex, the components of whic...

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Hlavní autoři: Gao, Peng, Yoo, Seung-Hee, Lee, Kyung-Jong, Rosensweig, Clark, Takahashi, Joseph S., Chen, Benjamin P., Green, Carla B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853276/
https://ncbi.nlm.nih.gov/pubmed/24158435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.509604
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