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Promiscuous Activation of Transient Receptor Potential Vanilloid 1 (TRPV1) Channels by Negatively Charged Intracellular Lipids: THE KEY ROLE OF ENDOGENOUS PHOSPHOINOSITIDES IN MAINTAINING CHANNEL ACTIVITY

The regulation of the heat- and capsaicin-activated transient receptor potential vanilloid 1 (TRPV1) channels by phosphoinositides is controversial. Data in cellular systems support the dependence of TRPV1 activity on phosphoinositides. The purified TRPV1, however, was recently shown to be fully fun...

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Detalles Bibliográficos
Main Authors: Lukacs, Viktor, Rives, Jan-Michael, Sun, Xiaohui, Zakharian, Eleonora, Rohacs, Tibor
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853253/
https://ncbi.nlm.nih.gov/pubmed/24158445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.520288
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