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Characterization of Structure, Dynamics, and Detergent Interactions of the Anti-HIV Chemokine Variant 5P12-RANTES

RANTES (CCL5) is a chemokine that recruits immune cells to inflammatory sites by interacting with the G-protein coupled receptor CCR5, which is also the primary coreceptor used together with CD4 by HIV to enter and infect target cells. Ligands of CCR5, including chemokines and chemokine analogs, are...

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Hlavní autoři: Wiktor, Maciej, Hartley, Oliver, Grzesiek, Stephan
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853082/
https://ncbi.nlm.nih.gov/pubmed/24314089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.10.025
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