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Characterization of Structure, Dynamics, and Detergent Interactions of the Anti-HIV Chemokine Variant 5P12-RANTES

RANTES (CCL5) is a chemokine that recruits immune cells to inflammatory sites by interacting with the G-protein coupled receptor CCR5, which is also the primary coreceptor used together with CD4 by HIV to enter and infect target cells. Ligands of CCR5, including chemokines and chemokine analogs, are...

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Autori principali: Wiktor, Maciej, Hartley, Oliver, Grzesiek, Stephan
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853082/
https://ncbi.nlm.nih.gov/pubmed/24314089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.10.025
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