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“Jumpstart and gain” model for dosage compensation in Drosophila based on direct sequencing of nascent transcripts
Dosage compensation in Drosophila is mediated by the MSL complex, which increases male X-linked gene expression approximately two-fold. The MSL complex preferentially binds the bodies of active genes on the male X, depositing H4K16ac with a 3′ bias. Two models have been proposed for the influence of...
Tallennettuna:
| Päätekijät: | , , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3852897/ https://ncbi.nlm.nih.gov/pubmed/24183666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.09.037 |
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