Synthesis, characterization, and evaluation of a novel inhibitor of WNT/β-catenin signaling pathway

BACKGROUND: Wnt/β-catenin signaling is a highly conserved pathway in organism evolution and is important in many biological processes. Overactivation of Wnt/β-catenin signaling is closely related to tumor development and progression. To identify potent small molecules that can fight aberrant Wnt/β-c...

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Autori principali: Yan, Zhao, Zhu, Zhongling, Wang, Jinghui, Sun, Jian, Chen, Yihui, Yang, Guang, Chen, Wenting, Deng, Yuheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852836/
https://ncbi.nlm.nih.gov/pubmed/24098916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-116
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