The soluble Decoy Receptor 3 is regulated by a PI3K-dependent mechanism and promotes migration and invasion in renal cell carcinoma

BACKGROUND: Overexpression of Decoy Receptor 3 (DcR3), a soluble member of the tumor necrosis factor receptor superfamily, is a common event in several types of cancer. In renal cell carcinoma (RCC), DcR3 overexpression is associated with lymph node and distant metastasis as well as a poor prognosis...

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Bibliografiska uppgifter
Huvudupphovsmän: Weissinger, Daniel, Tagscherer, Katrin E, Macher-Göppinger, Stephan, Haferkamp, Axel, Wagener, Nina, Roth, Wilfried
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2013
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852559/
https://ncbi.nlm.nih.gov/pubmed/24107265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-120
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