Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria.
Expression of the human protooncogene bcl-2 protects neural cells from death induced by many forms of stress, including conditions that greatly elevate intracellular Ca2+. Considering that Bcl-2 is partially localized to mitochondrial membranes and that excessive mitochondrial Ca2+ uptake can impair...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1996
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38525/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8790427/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.18.9893 |
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