Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria.

Expression of the human protooncogene bcl-2 protects neural cells from death induced by many forms of stress, including conditions that greatly elevate intracellular Ca2+. Considering that Bcl-2 is partially localized to mitochondrial membranes and that excessive mitochondrial Ca2+ uptake can impair...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Murphy, A N, Bredesen, D E, Cortopassi, G, Wang, E, Fiskum, G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38525/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8790427/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.18.9893
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