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BMP2 Induces Osteoblast Apoptosis in a Maturation State and Noggin-dependent Manner

Large doses of bone morphogenetic protein 2 (BMP2) are used clinically to induce bone formation in challenging bone defects. However, complications after treatment include swelling, ectopic bone formation, and adjacent bone resorption. While BMP2 can be effective, it is important to characterize the...

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Detalhes bibliográficos
Main Authors: Hyzy, Sharon L., Olivares-Navarrete, Rene, Schwartz, Zvi, Boyan, Barbara D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852427/
https://ncbi.nlm.nih.gov/pubmed/22628200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.24201
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