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Evaluating human cancer cell metastasis in zebrafish

BACKGROUND: In vivo metastasis assays have traditionally been performed in mice, but the process is inefficient and costly. However, since zebrafish do not develop an adaptive immune system until 14 days post-fertilization, human cancer cells can survive and metastasize when transplanted into zebraf...

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Detalhes bibliográficos
Main Authors: Teng, Yong, Xie, Xiayang, Walker, Steven, White, David T, Mumm, Jeff S, Cowell, John K
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852235/
https://ncbi.nlm.nih.gov/pubmed/24089705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-453
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