COP1 and GSK3β Cooperate to Promote c-Jun Degradation and Inhibit Breast Cancer Cell Tumorigenesis

High abundance of c-Jun is detected in invasive breast cancer cells and aggressive breast tumor malignancies. Here, we demonstrate that a major cause of high c-Jun abundance in invasive breast cancer cells is prolonged c-Jun protein stability owing to poor poly-ubiquitination of c-Jun. Among the kno...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Shao, Jing, Teng, Yong, Padia, Ravi, Hong, Sungguan, Noh, Hyangsoon, Xie, Xiayang, Mumm, Jeff S, Dong, Zheng, Ding, Han-Fei, Cowell, John, Kim, Jaejik, Han, Jiahuai, Huang, Shuang
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769886/
https://ncbi.nlm.nih.gov/pubmed/24027432
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados