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A superfolding Spinach2 reveals the dynamic nature of trinucleotide repeat RNA

Fluorescent imaging of RNA in living cells is a technically challenging problem in cell biology. One strategy for genetically encoding fluorescent RNAs is to express them as fusions with ‘RNA mimics of GFP’. These are short aptamer tags that exhibit fluorescence upon binding otherwise nonfluorescent...

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Bibliographic Details
Main Authors: Strack, Rita L., Disney, Matthew D., Jaffrey, Samie R.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852148/
https://ncbi.nlm.nih.gov/pubmed/24162923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2701
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