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Canonical Wnt/β-Catenin Signalling Is Essential for Optic Cup Formation

A multitude of signalling pathways are involved in the process of forming an eye. Here we demonstrate that β-catenin is essential for eye development as inactivation of β-catenin prior to cellular specification in the optic vesicle caused anophthalmia in mice. By achieving this early and tissue-spec...

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Autors principals: Hägglund, Anna-Carin, Berghard, Anna, Carlsson, Leif
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852023/
https://ncbi.nlm.nih.gov/pubmed/24324671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081158
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