Genome-Wide Association Study for Levels of Total Serum IgE Identifies HLA-C in a Japanese Population

Most of the previously reported loci for total immunoglobulin E (IgE) levels are related to Th2 cell-dependent pathways. We undertook a genome-wide association study (GWAS) to identify genetic loci responsible for IgE regulation. A total of 479,940 single nucleotide polymorphisms (SNPs) were tested...

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Detalhes bibliográficos
Main Authors: Yatagai, Yohei, Sakamoto, Tohru, Masuko, Hironori, Kaneko, Yoshiko, Yamada, Hideyasu, Iijima, Hiroaki, Naito, Takashi, Noguchi, Emiko, Hirota, Tomomitsu, Tamari, Mayumi, Imoto, Yoshimasa, Tokunaga, Takahiro, Fujieda, Shigeharu, Konno, Satoshi, Nishimura, Masaharu, Hizawa, Nobuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851760/
https://ncbi.nlm.nih.gov/pubmed/24324648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080941
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