Genetic association of the functional CDHR3 genotype with early-onset adult asthma in Japanese populations

Background: Recent studies have demonstrated that a coding SNP (rs6967330, Cys529→Tyr) in cadherin-related family member 3 (CDHR3), which was previously associated with wheezing illness and hospitalizations in infancy, could support efficient human rhinovirus C (RV-C) entry and replication. Here, we...

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Main Authors: Jun Kanazawa, Hironori Masuko, Yohei Yatagai, Tohru Sakamoto, Hideyasu Yamada, Yoshiko Kaneko, Haruna Kitazawa, Hiroaki Iijima, Takashi Naito, Takefumi Saito, Emiko Noguchi, Satoshi Konno, Masaharu Nishimura, Tomomitsu Hirota, Mayumi Tamari, Nobuyuki Hizawa
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2017-10-01
Serija:Allergology International
Teme:
Asthma phenotype
Cadherin-related family member 3 (CDHR3)
Early-onset asthma
Genetics
Human rhinovirus C
Online dostop:http://www.sciencedirect.com/science/article/pii/S1323893017300163
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