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MicroRNAs as the cause of schizophrenia in 22q11.2 deletion carriers, and possible implications for idiopathic disease: a mini-review

The 22q11.2 deletion is the strongest known genetic risk factor for schizophrenia. Research has implicated microRNA-mediated dysregulation in 22q11.2 deletion syndrome (22q11.2DS) schizophrenia-risk. Primary candidate genes are DGCR8 (DiGeorge syndrome critical region gene 8), which encodes a compon...

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Detalhes bibliográficos
Main Authors: Forstner, Andreas J., Degenhardt, Franziska, Schratt, Gerhard, Nöthen, Markus M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851736/
https://ncbi.nlm.nih.gov/pubmed/24367288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2013.00047
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