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Fundamental Reaction Pathway for Peptide Metabolism by Proteasome: Insights from First-principles Quantum Mechanical/Molecular Mechanical Free Energy Calculations

Proteasome is the major component of the crucial nonlysosomal protein degradation pathway in the cells, but the detailed reaction pathway is unclear. In this study, first-principles quantum mechanical/molecular mechanical free energy calculations have been performed to explore, for the first time, p...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wei, Donghui, Fang, Lei, Tang, Mingsheng, Zhan, Chang-Guo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851579/
https://ncbi.nlm.nih.gov/pubmed/24111489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp405337v
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