HINT1 protein cooperates with cannabinoid 1 receptor to negatively regulate glutamate NMDA receptor activity

BACKGROUND: G protein-coupled receptors (GPCRs) are the targets of a large number of drugs currently in therapeutic use. Likewise, the glutamate ionotropic N-methyl-D-aspartate receptor (NMDAR) has been implicated in certain neurological disorders, such as neurodegeration, neuropathic pain and mood...

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Main Authors: Vicente-Sánchez, Ana, Sánchez-Blázquez, Pilar, Rodríguez-Muñoz, María, Garzón, Javier
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851374/
https://ncbi.nlm.nih.gov/pubmed/24093505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-6-42
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