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Differential reconstructed gene interaction networks for deriving toxicity threshold in chemical risk assessment

BACKGROUND: Pathway alterations reflected as changes in gene expression regulation and gene interaction can result from cellular exposure to toxicants. Such information is often used to elucidate toxicological modes of action. From a risk assessment perspective, alterations in biological pathways ar...

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Detalhes bibliográficos
Main Authors: Yang, Yi, Maxwell, Andrew, Zhang, Xiaowei, Wang, Nan, Perkins, Edward J, Zhang, Chaoyang, Gong, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851258/
https://ncbi.nlm.nih.gov/pubmed/24268022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-S14-S3
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