Ocular Disposition of the Hemiglutarate Ester Prodrug of ∆(9)-Tetrahydrocannabinol from Various Ophthalmic Formulations

PURPOSE: The overall goal of this project is to enhance ocular delivery of ∆(9)-Tetrahydrocannabinol (THC) through the topical route. METHODS: Solubility, stability and in vitro transcorneal permeability of the relatively hydrophilic hemiglutarate ester derivative, THC-HG, was studied in the presenc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hingorani, Tushar, Adelli, Goutham R., Punyamurthula, Nagendra, Gul, Waseem, ElSohly, Mahmoud A., Repka, Michael A., Majumdar, Soumyajit
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851110/
https://ncbi.nlm.nih.gov/pubmed/23737345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-013-1072-x
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