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Loss of Imprinting of IGF2 as an Epigenetic Marker for the Risk of Human Cancer

IGF2 is the first gene discovered to be imprinted and expressed exclusively from the paternal allele in both human and mouse. IGF2 is also the first imprinted gene displaying loss of imprinting (LOI) or aberrant imprinting in human cancers. Evidently, LOI or reactivation of the maternal allele of IG...

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Detalhes bibliográficos
Autor principal: Cui, Hengmi
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851053/
https://ncbi.nlm.nih.gov/pubmed/17325430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2007/363464
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