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Loss of IGF2 imprinting is associated with abrogation of long-range intrachromosomal interactions in human cancer cells

Nuclear architecture and chromatin geography are important factors in the regulation of gene expression, as these components may play a vital epigenetic role both in normal physiology as well as in the initiation and progression of malignancies. Using a modification of the chromosome conformation ca...

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Detalhes bibliográficos
Main Authors: Vu, Thanh H., Nguyen, An H., Hoffman, Andrew R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816615/
https://ncbi.nlm.nih.gov/pubmed/20015958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp558
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