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Distribution of Recombination Crossovers and the Origin of Haplotype Blocks: The Interplay of Population History, Recombination, and Mutation

Recent studies suggest that haplotypes are arranged into discrete blocklike structures throughout the human genome. Here, we present an alternative haplotype block definition that assumes no recombination within each block but allows for recombination between blocks, and we use it to study the combi...

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Detalhes bibliográficos
Main Authors: Wang, Ning, Akey, Joshua M., Zhang, Kun, Chakraborty, Ranajit, Jin, Li
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC385104/
https://ncbi.nlm.nih.gov/pubmed/12384857
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