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Crossovers are associated with mutation and biased gene conversion at recombination hotspots
Meiosis is a potentially important source of germline mutations, as sites of meiotic recombination experience recurrent double-strand breaks (DSBs). However, evidence for a local mutagenic effect of recombination from population sequence data has been equivocal, likely because mutation is only one o...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4343121/ https://ncbi.nlm.nih.gov/pubmed/25646453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1416622112 |
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