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MACROPHAGES ARE UNSUCCESSFUL IN CLEARING AGGREGATED ALPHA-SYNUCLEIN FROM THE GASTROINTESTINAL TRACT OF HEALTHY AGED FISCHER 344 RATS
With age, alpha-synuclein (α-SYNC) misfolds and forms insoluble deposits of protein in the myenteric plexus, leading presumably to dystrophy and degeneration in the circuitry controlling gastrointestinal (GI) function. The present experiment examined aggregates of α-SYNC in the aging small intestine...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3851024/ https://ncbi.nlm.nih.gov/pubmed/23441091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ar.22675 |
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