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Sarcoidosis Th17 Cells are ESAT-6 Antigen Specific but Demonstrate Reduced IFN-γ Expression

RATIONALE: Sarcoidosis is a granulomatous disease of unknown etiology. Many patients with sarcoidosis demonstrate antigen-specific immunity to mycobacterial virulence factors. Th-17 cells are crucial to the immune response in granulomatous inflammation, and have recently been shown to be present in...

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Detalhes bibliográficos
Main Authors: Richmond, Bradley W., Ploetze, Kristen, Isom, Joan, Chambers-Harris, Isfahan, Braun, Nicole A., Taylor, Thyneice, Abraham, Susamma, Mageto, Yolanda, Culver, Dan A., Oswald-Richter, Kyra A., Drake, Wonder P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3850764/
https://ncbi.nlm.nih.gov/pubmed/23073617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10875-012-9817-6
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