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Isolation, Structural Elucidation, and Absolute Stereochemistry of Enigmazole A, a Cytotoxic Phosphomacrolide from the Papua New Guinea Marine Sponge Cinachyrella enigmatica

Enigmazole A (1), a novel phosphate-containing macrolide, was isolated from a Papua New Guinea collection of the marine sponge Cinachyrella enigmatica. The structure of 1, including the absolute stereochemistry at all eight chiral centers, was determined by a combination of spectroscopic analyses an...

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Библиографические подробности
Главные авторы: Oku, Naoya, Takada, Kentaro, Fuller, Richard W., Wilson, Jennifer A., Peach, Megan L., Pannell, Lewis K., McMahon, James B., Gustafson, Kirk R.
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3850515/
https://ncbi.nlm.nih.gov/pubmed/20590096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1016766
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