Mimotope vaccination for epitope-specific induction of anti-VEGF antibodies

BACKGROUND: Tumor angiogenesis is critical for tumor growth, infiltration and metastasis. Vascular endothelial growth factor (VEGF) is a potent angiogenic factor and targeting it is important in reducing angiogenesis. Bevacizumab (Avastin), a monoclonal antibody that reacts directly against VEGF, ha...

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Bibliographische Detailangaben
Hauptverfasser: Li, Weina, Ran, Yonggang, Li, Meng, Zhang, Kuo, Qin, Xin, Xue, Xiaochang, Zhang, Cun, Hao, Qiang, Zhang, Wei, Zhang, Yingqi
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849980/
https://ncbi.nlm.nih.gov/pubmed/24073737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-13-77
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