Intracytoplasmic Sperm Injection May Increase the Risk of Imprinting Defects

In germ cells and the early embryo, the mammalian genome undergoes widespread epigenetic reprogramming. Animal studies suggest that this process is vulnerable to external factors. We report two children who were conceived by intracytoplasmic sperm injection (ICSI) and who developed Angelman syndrome...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cox, Gerald F., Bürger, Joachim, Lip, Va, Mau, Ulrike A., Sperling, Karl, Wu, Bai-Lin, Horsthemke, Bernhard
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society of Human Genetics 2002
Gaiak:
Report
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC384973/
https://ncbi.nlm.nih.gov/pubmed/12016591
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