Deregulated expression of TANK in glioblastomas triggers pro-tumorigenic ERK1/2 and AKT signaling pathways

Signal transmission by the noncanonical IkappaB kinases (IKKs), TANK-binding kinase 1 (TBK1) and IKKɛ, requires interaction with adapter proteins such as TRAF associated NF-κB activator (TANK). Although increased expression or dysregulation of both kinases has been described for a variety of human c...

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Autors principals: Stellzig, J, Chariot, A, Shostak, K, Ismail Göktuna, S, Renner, F, Acker, T, Pagenstecher, A, Schmitz, M L
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849693/
https://ncbi.nlm.nih.gov/pubmed/24217713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2013.42
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