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Sleep Homeostasis Modulates Hypocretin-Mediated Sleep-to-Wake Transitions

The hypocretins (Hcrts) (also called orexins) are two neuropeptides expressed in the lateral hypothalamus that play a crucial role in the stability of wakefulness. Previously, our laboratory demonstrated that in vivo photostimulation of Hcrt neurons genetically targeted with ChR2, a light-activated...

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Autori principali: Carter, Matthew E., Adamantidis, Antoine, Ohtsu, Hiroshi, Deisseroth, Karl, de Lecea, Luis
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849591/
https://ncbi.nlm.nih.gov/pubmed/19726652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1205-09.2009
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