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Mechanism for Hypocretin-mediated sleep-to-wake transitions
Current models of sleep/wake regulation posit that Hypocretin (Hcrt)-expressing neurons in the lateral hypothalamus promote and stabilize wakefulness by projecting to subcortical arousal centers. However, the critical downstream effectors of Hcrt neurons are unknown. Here we use optogenetic, pharmac...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465396/ https://ncbi.nlm.nih.gov/pubmed/22955882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1202526109 |
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