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Sequence and structure based models of HIV-1 protease and reverse transcriptase drug resistance

BACKGROUND: Successful management of chronic human immunodeficiency virus type 1 (HIV-1) infection with a cocktail of antiretroviral medications can be negatively affected by the presence of drug resistant mutations in the viral targets. These targets include the HIV-1 protease (PR) and reverse tran...

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Detalhes bibliográficos
Main Authors: Masso, Majid, Vaisman, Iosif I
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849442/
https://ncbi.nlm.nih.gov/pubmed/24268064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-S4-S3
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