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Changes in Cellular mRNA Stability, Splicing and Polyadenylation through HuR Protein Sequestration by a Cytoplasmic RNA Virus

The impact of RNA viruses on the post-transcriptional regulation of cellular gene expression is unclear. Sindbis virus causes a dramatic relocalization of the cellular HuR protein from the nucleus to the cytoplasm in infected cells. This is due to the expression of large amounts of viral RNAs that c...

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Detaylı Bibliyografya
Asıl Yazarlar: Barnhart, Michael D., Moon, Stephanie L., Emch, Alexander W., Wilusz, Carol J., Wilusz, Jeffrey
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849337/
https://ncbi.nlm.nih.gov/pubmed/24210824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.10.012
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